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Department of Paediatric Nephrology |
Great Ormond Street Hospital for Children NHS Trust
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Patients were first dialysed here in 1985 .
This unit has 16 haemodialysis and 25 peritoneal dialysis patients.
| Contact Information: | |
| Telephone number: | 020 7405 9200 extension 0292 |
| Holiday dialysis enquiries: | 020 7829 8817 |
| Fax: | 020 7829 8841 |
| Email Address: | markss2@gosh.nhs.uk  |
| Unit website: | URL |
| Trust website: | http://www.gosh.nhs.uk |
| Consultants: | |
Dr Detlef Bockenhauer |
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Dr Stephen Marks |
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Dr Lesley Rees |
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Dr Richard Trompeter |
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| Dr Kjell Tullus | |
| Dr William van't Hoff | |
| Dr Paul Winyard | |
| Professor Adrian Woolf |
About the unit:
The unit provides a comprehensive inpatient and outpatient service for children with kidney disease, including acute and chronic renal failure. There is an active end-stage renal failure programme which includes treatment of infants, young children and adolescents with chronic and end-stage renal failure (dialysis (PD / haemodialysis) and live-related and deceased donor renal transplantation).
The renal unit works very closely with the urological service providing comprehensive management of infants and children with complex nephro-urological disorders.
The unit comprises a 16-bedded ward, Victoria Ward. The Renal Transplant Unit (Transplant Support Unit) and Haemodialysis Unit are nearby and we share patients with our urology colleagues. Day cases are also seen on the Medical Day Care and Programmed Investigations Unit (Kingfisher Ward and Island Day Care Unit).
The unit has special expertise in the investigation and management of every aspect of Paediatric Nephrology with special expertise in congenital renal anomalies, nephrotic syndrome, haemolytic uraemic syndrome, hypertension, vasculitis, tubular, metabolic and stone disorders.
Strong working links exist with Paediatric Urology, Radiology and Pathology. In addition, there are outreach links with a large number of teaching and district general paediatric departments. Surgical care of the end-stage renal failure (ESRF) patients is provided by a team of four transplant surgeons. The renal ward (Victoria) is managed by a senior sister; there are five clinical nurse specialists (CNS) for ESRF patients, a CNS who is responsible for co-ordinating the living donor programme, a CNS in charge of the plasma exchange programme, a senior and two other renal dieticians, a senior pharmacist, clinical psychologist, consultant family therapist, nurse counsellor, social worker, teacher and two play therapists. Research and special expertise Our mission in our Nephro-Urology Research Unit is to improve the diagnosis, treatment and prognosis of children with kidney and urinary tract diseases by investigating the underlying causes and mechanisms of initiation and progression of these conditions with high quality basic science and clinical research.
The Nephro-Urology Unit was formed in 1997 and moved into its extensively refurbished laboratory in 1998. The unit currently comprises a Unit Head (Adrian Woolf, Professor of Nephrology), one Senior Lecturer in Nephrology (Paul Winyard), four post-doctoral research fellows, three clinical research fellows and four graduate students. There are extensive laboratory facilities for molecular and cellular biology within the unit with strong links to affiliated laboratories including the Clinical and Molecular Genetics and Molecular Medicine Units, as well as with clinical staff in the Nephrology and Urology Departments within Great Ormond Street Hospital and with the Fetal Medicine Unit at University College Hospital.
Current active projects within the unit include investigations into: the genetics and cell biology of normal and abnormal development of the kidney and urinary tract; the reconstruction and functional restoration of abnormal genitourinary tracts; the renal vasculature and hypertension; nephrotic syndrome and vasculitis; the clinical consequences and treatment of kidney failure in children; control of differentiation of epithelial and endothelial cell lineages; genetics and cell biology of renal tubular disease; nutrition, growth and bone turnover in children with renal failure. In addition, we have been very successful in academic training of PhD, MD, MSc and both national and international visiting fellows. The unit also organises and hosts the prestigious annual Paediatric Nephrology and Urology week and initiated the Kidney Development workshop, which has now expanded into the yearly European Nephrogenesis workshop.
We receive funding from the Kidney Research UK, Kids Kidney Appeal, Action Research, the Medical Research Council, the Wellcome Trust and several other sources.
GOS Research http://www.ich.ucl.ac.uk/gosh/clinicalservices/Nephrology/Research http://www.ich.ucl.ac.uk/gosh/clinicalservices/Nephrology/RecentPublications
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